Findings were objectively assessed using advanced 3D skin topography analysis and ultrasound imaging.
Categories: Recovery Research
BPC-157 -5mg
4.9 (56 reviews)
$40
A synthetic peptide derived from a naturally occurring gastric protein. Studied in preclinical models for its potential role in tissue repair, angiogenesis, and cellular recovery mechanisms.
$40
In stock
Anti-Aging Compound
BPC-157 -5mg
In stock
4.9 (56 reviews)
Copper Tripeptide-1
Glycyl-L-histidyl-L-lysine Copper C
A synthetic peptide derived from a naturally occurring gastric protein. Studied in preclinical models for its potential role in tissue repair, angiogenesis, and cellular recovery mechanisms.
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📈
70%
COLLAGEN INCREASE
vs 50% vitamin C, 40% retinoic acid
🧬
31.2%
Genes Modulated
4,000+ human genes affected
💇
30-50%
Hair Growth
Follicle size increase
⏱️
12 WEEKS
Visible Results
Clinical facial study duration
NAD+ 500mg
NAD+ 500mg that modulates delta-wave sleep architecture and circadian rhythm signaling, studied for sleep onset mechanisms in research models. Premium Research Peptide.
Original price was: $70.$39Current price is: $39.
Certificate of Analysis
Third Party Tested by Freedom Diagnostics
Key Discovery
Advanced Influence on Gene Expression
GHK-Cu affects more human genes than any other studied peptide — modulating 31.2% of the human genome.
Research finding: GHK-Cu increased expression of 1,942 genes and suppressed 762 genes in human fibroblasts, affecting pathways from DNA repair to antioxidant defense.
Genes Upregulated 1,942
Genes Upregulated 762
DNA Repair Genes ↑ 47 genes
Antioxidant Genes ↑ 14 genes
The Science, Simplified
Certificate of Analysis
GHK-Cu is a naturally occurring tripeptide that binds with copper to create a powerful regenerative complex. Released from damaged collagen as an injury signal, it orchestrates healing by modulating thousands of genes involved in tissue repair, inflammation control, and cellular protection.
GE
Primary
Gene Expression
Epigenetic Modulation
Upregulates 59% of affected genes, Activates 47 DNA repair genes, and suppresses inflammatory pathways
COL
Strongest
Collagen Pathway
Collagen & ECM Synthesis
Stimulates type I & III collagen
Increases elastin production
Enhances ECM remodeling
Cu²⁺
Supportive
Copper Delivery
Copper Ion Transport
Delivers copper to cells
Activates SOD antioxidant
Supports wound healing enzymes
📊
What Research Has Shown
Overview of Clinical and Preclinical Findings
📋 12-Week Facial Study — 71 Women
55.8%
Wrinkle Volume Reduction
Wrinkle Reduction Comparison
Trial details: In a 12-week study, 71 women with mild to advanced photoaging applied GHK-Cu facial cream twice daily, with outcomes assessed via skin density, elasticity, and 3D wrinkle analysis.
📈 Clinical Outcomes
Key Trial Results
Objective measurements from clinical studies
Note:
⚖️ Comparison
Collagen Stimulation Comparison
Note: Findings are based on thigh skin biopsy analyses quantifying collagen production after one month of treatment
📋 Plasma Concentration Studies
Age-Related Decline in Natural GHK Levels
Natural GHK-Cu levels decrease significantly with age
✨
Beyond Skin Rejuvenation
Other benefits observed in research
Hair
Growth
30-50% follicle size increase
Wound
Healing
Enhanced diabetic ulcer healing
47
DNA Repair Genes
Activated for cellular protection
Anti
Inflammatory
Reduced TNF-α and IL-6
💇 Hair Restoration
Follicle Regeneration
Research shows GHK-Cu significantly improves hair growth parameters
Study finding: GHK-Cu increased hair follicle size by 30-50% compared to placebo in controlled studies.
🩹 Wound Healing
Tissue Repair Acceleration
Multiple pathways contribute to enhanced healing
Angiogenesis ↑ Enhanced
Fibroblast migration ↑ 70% faster
Collagen deposition ↑ Increased
Inflammatory response ↓ Reduced
Clinical evidence: Diabetic ulcer patients showed significantly improved healing with topical GHK-Cu treatment.
🧬 Gene Modulation
Epigenetic Reprogramming
GHK-Cu acts as a master regulator of cellular health
4,000+
Genes Affected
Key insight: GHK-Cu shifts gene expression patterns from tissue destruction to tissue repair, affecting pathways involved in aging and regeneration.
🛡️ Antioxidant Defense
cellular protection
Multiple mechanisms combat oxidative stress
SOD activity ↑ Increased
Catalase expression ↑ Enhanced
Free radical scavenging ↑ Improved
Lipid peroxidation ↓ -38%
⚠️
Safety Profile from Research
What clinical studies report
What clinical studies report
GHK-Cu has demonstrated an excellent safety profile across multiple studies with minimal adverse effects
🤢 Common Digestive Issues
5%
Injection site irritation
MILD
3%
Skin redness (topical)
MILD
2%
Itching
MILD
⚠️ Theoretical Concern
Copper Accumulation Risk
Copper toxicity is theoretically possible with extreme overuse but has not been reported in clinical studies
- Normal therapeutic doses well below toxic threshold
- Body has efficient copper regulation mechanisms
- No cases reported in published literature at research doses
📊 Discontinuation Rates
Treatment discontinuation Rates
Topical 2-4% <1%
Injectable 1-2mg 2%
Extremely low discontinuation rates across all studies
Most discontinuations due to protocol non-compliance, not adverse effects
🚫 Trial Exclusions
Study Exclusion criteria
- Wilson's disease (copper metabolism disorder)
- Known copper allergy
- Active skin infections at application site
- Pregnancy or breastfeeding (not studied)
Wilson's disease (copper metabolism disorder)
Known copper allergy
🧪
Compound Information
Technical specifications
🔬 Molecular Profile
What Is NAD+?
Type
Coenzyme (Nicotinamide Adenine Dinucleotide)
COA Number
2601300229
Roles
Cellular energy & metabolic regulator
Function
Essential for ATP (energy) production
Amino Acids
3 (tripeptide)
Sequence
NADH - NMN - NR
Formula
C₂₁H₂₇N₇O₁₄P₂
🧊 Storage Requirements
Stability Information
Protect from light
Avoid excessive heat
Blue color indicates copper binding
❄️
Lyophilized (powder)
-20°C • up to 2 years
💉
Reconstituted
2-8°C • up to 30 days
💉
Working solution
Use within 24 hours
📋 Research Status
Where It Stands
Naturally Occurring
Protect from light
Longevity Research Focus
Origin
Human plasma
Primary research
Regenerative medicine
Clinical studies
50+ published
Commercial use
Cosmetics since 1980s
❓
Frequently Asked Questions
What are these products intended for?
All products listed on this website are intended strictly for laboratory research purposes only. They are not approved for human consumption, medical use, or diagnostic applications.
Are your products tested for purity?
Yes. Every batch undergoes third-party laboratory testing to verify purity, identity, and quality. Certificates of Analysis (COA) are available for transparency.
What is the typical purity level?
Our products are tested to achieve ≥99% purity (HPLC verified), ensuring consistency and reliability for research applications.
Do you provide Certificates of Analysis (COA)?
Yes. Each product batch includes a COA from an independent laboratory, confirming purity and quality metrics.
How should products be stored?
Products should be stored in a cool, dry environment, away from direct light. For extended stability, refrigeration is recommended after reconstitution (for research handling).
How long does shipping take?
Orders are processed promptly, with fast and reliable shipping options available. Delivery times vary depending on location and selected shipping method.
📚
Sources & References
Peer-reviewed research
International Journal of Molecular Sciences
Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data
2018•PMID: 29986520
Pickart L, Margolina A
BioMed Research International
GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration
2015•PMID: 26236730
Pickart L, Vasquez-Soltero JM, Margolina A
Journal of Cosmetic Science
A 12-week, double-blind, placebo-controlled study of GHK-Cu facial cream
2005
Finkley et al.
Journal of Cosmetic Laser Therapy
Stimulation of collagen production by copper-peptide complex
2007
Appa Y et al.
Journal of Aging Science and Clinical Practice
Effects of GHK-Cu in nano-carriers on MMP expression and facial wrinkle parameters
2019
Gorouhi F, Maibach HI
Archives of Facial Plastic Surgery
Effects of Topical Copper Tripeptide Complex on CO2 Laser-Resurfaced Skin
2006 • DOI: 10.1001/archfaci.8.4.252
Miller TR et al.
Various Sources
GHK-Cu effects on hair follicle growth and size
2020
Multiple researchers
Multiple Sources
GHK-Cu dosing and administration protocols
2018
Various clinical trials
Journal of Cosmetic Dermatology
Anti-inflammatory effects of GHK-Cu
2012
Campbell JD et al.
research use only
Not for human consumption. This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.
All clinical trial data and research findings presented on this page are sourced from peer-reviewed journals and official publications. They are provided for educational reference only and should not be interpreted as medical advice or product claims.
By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations.
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