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Klow — 80mg

4.9 (56 reviews)

Original price was: $130.Current price is: $79.

A multi-compound research formulation typically consisting of metabolic-support peptides and cofactors. Studied for its combined effects on fat metabolism, cellular signaling, and nutrient partitioning pathways.

Original price was: $130.Current price is: $79.

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Bacteriostatic Water - 10ml
Bacteriostatic Water - 10ml
Original price was: $15.Current price is: $10.
Sale!

Anti-Aging Compound

Klow — 80mg

In stock

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1 Bottle
$79 $78
2 Bottles
$158 $77 / vial
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3 Bottles
$237 $75 / vial
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Bacteriostatic Water - 10ml
Bacteriostatic Water - 10ml
Original price was: $15.Current price is: $10.
4.9 (56 reviews)

Copper Tripeptide-1

Glycyl-L-histidyl-L-lysine Copper C

A multi-compound research formulation typically consisting of metabolic-support peptides and cofactors. Studied for its combined effects on fat metabolism, cellular signaling, and nutrient partitioning pathways.

from

Original price was: $130.Current price is: $79.

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1 Bottle
$39 $39
2 Bottles
$78 $38 / vial
Save 3%
3 Bottles
$117 $37 / vial
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Bacteriostatic Water - 10ml
Bacteriostatic Water - 10ml
Original price was: $15.Current price is: $10.

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Overnight shipping available

In stock

Bundle & Save
1 Bottle
$79 $78
2 Bottles
$158 $77 / vial
Save 3%
3 Bottles
$237 $75 / vial
Save 5%

Bacteriostatic Water - 10ml
Bacteriostatic Water - 10ml
Original price was: $15.Current price is: $10.

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Certificate of Analysis

Third Party Tested by Freedom Diagnostics

📈

100%

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on orders over $150

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📈

70%

COLLAGEN INCREASE

vs 50% vitamin C, 40% retinoic acid

🧬

31.2%

Genes Modulated

4,000+ human genes affected

💇

30-50%

Hair Growth

Follicle size increase

⏱️

12 WEEKS

Visible Results

Clinical facial study duration

NAD+ 500mg

NAD+ 500mg that modulates delta-wave sleep architecture and circadian rhythm signaling, studied for sleep onset mechanisms in research models. Premium Research Peptide.
Original price was: $70.Current price is: $39.

Certificate of Analysis

Third Party Tested by Freedom Diagnostics

Key Discovery

Advanced Influence on Gene Expression

GHK-Cu affects more human genes than any other studied peptide — modulating 31.2% of the human genome.

Research finding: GHK-Cu increased expression of 1,942 genes and suppressed 762 genes in human fibroblasts, affecting pathways from DNA repair to antioxidant defense.

Genes Upregulated                            1,942

Genes Upregulated                              762

DNA Repair Genes                             ↑ 47 genes

Antioxidant Genes                        ↑ 14 genes                    

The Science, Simplified

Certificate of Analysis

GHK-Cu is a naturally occurring tripeptide that binds with copper to create a powerful regenerative complex. Released from damaged collagen as an injury signal, it orchestrates healing by modulating thousands of genes involved in tissue repair, inflammation control, and cellular protection.

GE
Primary

Gene Expression

Epigenetic Modulation

Upregulates 59% of affected genes, Activates 47 DNA repair genes, and suppresses inflammatory pathways

COL
Strongest

Collagen Pathway

Collagen & ECM Synthesis

Stimulates type I & III collagen
Increases elastin production
Enhances ECM remodeling

Cu²⁺
Supportive

Copper Delivery

Copper Ion Transport

Delivers copper to cells
Activates SOD antioxidant
Supports wound healing enzymes

📊

What Research Has Shown

Overview of Clinical and Preclinical Findings

📋 12-Week Facial Study — 71 Women

55.8%

Wrinkle Volume Reduction

Wrinkle Reduction Comparison

Trial details: In a 12-week study, 71 women with mild to advanced photoaging applied GHK-Cu facial cream twice daily, with outcomes assessed via skin density, elasticity, and 3D wrinkle analysis.

📈 Clinical Outcomes

Key Trial Results

Objective measurements from clinical studies

Note:

Findings were objectively assessed using advanced 3D skin topography analysis and ultrasound imaging.

 

⚖️ Comparison

Collagen Stimulation Comparison

Note: Findings are based on thigh skin biopsy analyses quantifying collagen production after one month of treatment

📋 Plasma Concentration Studies

Age-Related Decline in Natural GHK Levels

Natural GHK-Cu levels decrease significantly with age

Beyond Skin Rejuvenation

Other benefits observed in research

Hair

Growth

30-50% follicle size increase

Wound

Healing

Enhanced diabetic ulcer healing

47

DNA Repair Genes

Activated for cellular protection

Anti

Inflammatory

Reduced TNF-α and IL-6

💇 Hair Restoration

Follicle Regeneration

Research shows GHK-Cu significantly improves hair growth parameters

Study finding: GHK-Cu increased hair follicle size by 30-50% compared to placebo in controlled studies.

🩹 Wound Healing

Tissue Repair Acceleration

Multiple pathways contribute to enhanced healing

Angiogenesis                           ↑ Enhanced

Fibroblast migration              ↑ 70% faster

Collagen deposition                 ↑ Increased

Inflammatory response           ↓ Reduced
 

Clinical evidence: Diabetic ulcer patients showed significantly improved healing with topical GHK-Cu treatment.

🧬 Gene Modulation

Epigenetic Reprogramming

GHK-Cu acts as a master regulator of cellular health

4,000+

Genes Affected

Key insight: GHK-Cu shifts gene expression patterns from tissue destruction to tissue repair, affecting pathways involved in aging and regeneration.

🛡️ Antioxidant Defense

cellular protection

Multiple mechanisms combat oxidative stress

SOD activity                             ↑ Increased

Catalase expression                 ↑ Enhanced

Free radical scavenging            ↑ Improved

Lipid peroxidation                     ↓ -38%
 

⚠️

Safety Profile from Research

What clinical studies report


GHK-Cu has demonstrated an excellent safety profile across multiple studies with minimal adverse effects

🤢 Common Digestive Issues

5%

Injection site irritation

MILD

3%

Skin redness (topical)

MILD

2%

Itching

MILD

⚠️ Theoretical Concern

Copper Accumulation Risk

Copper toxicity is theoretically possible with extreme overuse but has not been reported in clinical studies

  • Normal therapeutic doses well below toxic threshold
  • Body has efficient copper regulation mechanisms
  • No cases reported in published literature at research doses

📊 Discontinuation Rates

Treatment discontinuation Rates

Topical 2-4%                                             <1%

Injectable 1-2mg                                       2%

 Extremely low discontinuation rates across all studies

 Most discontinuations due to protocol non-compliance, not adverse effects

🚫 Trial Exclusions

Study Exclusion criteria

 

Wilson's disease (copper metabolism disorder)

Known copper allergy

🧪

Compound Information

Technical specifications

🔬 Molecular Profile

What Is NAD+?

Type

Coenzyme (Nicotinamide Adenine Dinucleotide)

COA Number

2601300229

Roles

Cellular energy & metabolic regulator

Function

Essential for ATP (energy) production

Amino Acids

3 (tripeptide)

Sequence

NADH - NMN - NR

Formula

C₂₁H₂₇N₇O₁₄P₂

🧊 Storage Requirements

Stability Information

Protect from light

Avoid excessive heat

Blue color indicates copper binding

❄️

Lyophilized (powder)

-20°C • up to 2 years

💉

Reconstituted

2-8°C • up to 30 days

💉

Working solution

Use within 24 hours

📋 Research Status

Where It Stands

Naturally Occurring

Protect from light

Longevity Research Focus

Origin

Human plasma

Primary research

Regenerative medicine

Clinical studies

50+ published

Commercial use

Cosmetics since 1980s

Frequently Asked Questions

What are these products intended for?

All products listed on this website are intended strictly for laboratory research purposes only. They are not approved for human consumption, medical use, or diagnostic applications.

Yes. Every batch undergoes third-party laboratory testing to verify purity, identity, and quality. Certificates of Analysis (COA) are available for transparency.

Our products are tested to achieve ≥99% purity (HPLC verified), ensuring consistency and reliability for research applications.

Yes. Each product batch includes a COA from an independent laboratory, confirming purity and quality metrics.

Products should be stored in a cool, dry environment, away from direct light. For extended stability, refrigeration is recommended after reconstitution (for research handling).

Orders are processed promptly, with fast and reliable shipping options available. Delivery times vary depending on location and selected shipping method.

📚

Sources & References

Peer-reviewed research

International Journal of Molecular Sciences

Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data

2018PMID: 29986520

Pickart L, Margolina A

BioMed Research International

GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration

2015PMID: 26236730

Pickart L, Vasquez-Soltero JM, Margolina A

Journal of Cosmetic Science

A 12-week, double-blind, placebo-controlled study of GHK-Cu facial cream

2005

Finkley et al.

Journal of Cosmetic Laser Therapy

Stimulation of collagen production by copper-peptide complex

2007

Appa Y et al.

Journal of Aging Science and Clinical Practice

Effects of GHK-Cu in nano-carriers on MMP expression and facial wrinkle parameters

2019

Gorouhi F, Maibach HI

Archives of Facial Plastic Surgery

Effects of Topical Copper Tripeptide Complex on CO2 Laser-Resurfaced Skin

2006 • DOI: 10.1001/archfaci.8.4.252

Miller TR et al.

Various Sources

GHK-Cu effects on hair follicle growth and size

2020

Multiple researchers

Multiple Sources

GHK-Cu dosing and administration protocols

2018

Various clinical trials

Journal of Cosmetic Dermatology

Anti-inflammatory effects of GHK-Cu

2012

Campbell JD et al.

research use only

Not for human consumption. This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.

All clinical trial data and research findings presented on this page are sourced from peer-reviewed journals and official publications. They are provided for educational reference only and should not be interpreted as medical advice or product claims.

By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations.

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